shRNA Libraries
We offer high-quality, shRNA libraries based on your target gene list. These RNAi libraries can serve as powerful and cost-efficient tools for performing large-scale screens for genes involved in disease pathways, cell responses to drug treatment, developmental processes, and gene regulation.
Step 1) In silico shRNA prediction
3-4 weeks
Mirimus proprietary algorithm generates a list of shRNAs which are predicted to have the power to silence the gene of interest.
Step 2) In vitro validation
8-10 weeks
Mirimus proprietary assay assesses the gene silencing potency of those predicted shRNAs, generating a report with shRNA knock-down activities.
Step 3) Plasmids
2 weeks
The best shRNAs are delivered to the client in the form of lentiviral or retroviral plasmid backbones.